Zhao Bo, born in 1987, is a doctor of science, associate researcher and master's supervisor. From September 2004 to June 2008, he studied in Xinjiang University and obtained a bachelor's degree in engineering; From September 2010 to June 2015, he studied at the University of Chinese Academy of Sciences (Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences), and obtained a doctor degree in organic chemistry. From July 2015 to October 2020, he worked in the Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, as an assistant researcher; From November 2020 to now, he has worked in Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, as an associate researcher. Since 2013, he has been stationed in Tashkent branch of the Central Asian Drug Discovery and Development Center of the Chinese Academy of Sciences.
The main research areas
(1) Natural product chemistry and phytochemistry: separation, purification, structure identification and biological activity research of natural compounds;
(2) Pharmaceutical Chemistry: Research on drug quality standards, overseas registration of and clinical research drugs.
As a member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences, he is mainly engaged in the material basic research of the plants endemic in Central Asia, such as Aconitum and Delphinium. He has presided over 4 projects such as the Youth Fund of the National Natural Science Foundation of China and the Young Scholars of the West Light Foundation of the Chinese Academy of Sciences; and has participated 7 projects such as the National Key R & D Program, and the International Scientific and Technological Cooperation projects of the Xinjiang Uygur Autonomous Region. In the past five years, he published 11 SCI articles, applied for 2 patents, and assisted the research group in training 3 doctors and 1 master.
He has assisted the Central Asian Drug Discovery and Development Center of the Chinese Academy of Sciences to complete the registration of innovative drug Mindvy (Anti-SARS-CoV-2 oral drug), generic drug Sovonta (Anti hepatitis C drug), Cooperative R & D drug Rutan (Anti-SARS-CoV-2 oral drug), and characteristic traditional Chinese medicine Yizhihao granule (Anti-virus) in Uzbekistan. In addition, many drugs have been approved for clinical approval in Uzbekistan; Clinical research is being carried out.
Main Honors:
1) 2018, 2019 and 2020, Xinjiang Technical Institute of Physics and Chemistry of CAS, advanced worker;
2) 2021, Xinjiang Technical Institute of Physics and Chemistry of CAS, excellent Party member;
3) 2022, Xinjiang branch of the Chinese Academy of Sciences, excellent young workers.
Representative articles:
[1] B. Zhao, N. Ablajan, J. Y. Zhao, D. R. Kodirova, Sh.Sh. Sagdullaev, H.A. Aisa. Two new C19-diterpenoid alkaloids from Aconitum smirnovii, Phytochemistry Letters, 2020 (38): 96-100.
[2] B. Zhao, J. Y. Zhao, Sh. Sh. Sagdullaev, H. A. Aisa. Diterpene alkaloids from Aconitum smirnovii. Chemistry of Natural Compounds, 2018, 54 (4): 828-830.
[3] N. Ablajan, B. Zhao, W. J. Xue, J. Y. Zhao, Sh. Sh. Sagdullaev, G. A. Zou, H. A. Aisa. Chemical components of Aconitum barbatum var. puberulum and their cytotoxic and antibacterial activities. Natural Product Research, 2021 (publish online): DOI: 10.1080/14786419.2021.2005050.
[4] N. Ablajan, B. Zhao, J. Y. Zhao, B. L. Wang, Sh. Sh. Sagdullaev, H. A. Aisa. Diterpenoid alkaloids from Aconitum barbatum var. puberulum Ledeb, Phytochemistry, 2021 (181): 112567.
[5] W. J. Xue, B. Zhao, D. R. Kodirova, J. Y. Zhao, H. A. Aisa. Alkaloids from the plant Delphinium naviculare var. lasiocarpum, Chemistry of Natural Compounds, 2020, 56 (4):771-774.
[6] N. Ablajan, B. Zhao, J. Y. Zhao, D. R. Kodirova, Sh. Sh. Sagdullaev, H. A. Aisa. Alkaloids from Delphinium aemulans, Chemistry of Natural Compounds, 2020, 56 (5): 977-980.
[7] W. J. Xue, B. Zhao, J. Y. Zhao, Sh. Sh. Sagdullaev, H. A. Aisa. Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang, Phytochemistry Letters, 2019, 33: 12-16.
[8] W. J. Xue, B. Zhao, Z. Ruzi, J. Y. Zhao, H. A. Aisa. Norditerpenoid alkaloids from Delphinium pseudoaemulans C. Y. Yang et B.Wang. Phytochemistry, 2018, 156: 234-240.
[9] N. Ablajan, B. Zhao, W. J. Xue, Z. Ruzi, J. Y. Zhao, H. A. Aisa. Diterpenoid alkaloids from Delphinium aemulans. Natural Product Communications. 2018, 13 (11): 1429-1431.
[10]A. Samanbaya, B. Zhao, H. A. Aisa. A new denudatine type C20-diterpenoid alkaloid from Aconitum sinchiangense W. T. Wang. Natural Product Research. 2018, 32 (19): 2319-2324.
Representative patents:
Haji Akber Aisa, Waitaniguli Wali, Zhao Bo. The preparation method and use of diterpenoid alkaloids from Aconitum soongaricum var. pubescens. Patent No.: ZL201610281754.8.
Research areas：
Natural pharmaceutical chemistry, Phytochemistry, Pharmacy.
